C
Asthma D
Hypothesis: Iontophoresis will facilitate the
Three primary pathways exist for absorption through the SC: paracellular (between keratinocytes), transcellular (through keratinocytes), and appendageal (through hair follicles
Dexamethasone is the most commonly used medication with iontophoresis to treat a variety of connective tissue disorders
Average dexamethasone sodium phosphate (DSP) and dexamethasone (DXM) concentrations detected in skin dialysate following 20 min iontophoresis in
Dexamethasone is a corticosteroid medication often used with iontophoresis for reducing pain, swelling, and inflammation
Morbidity resulting from musculoskeletal pain contributes to 29%
Clinical Scenario: Iontophoresis is a method of local transfer of ionized medicated and nonmedicated substances through the skin and into the target tissues using magnetic polarization
Tissue was extracted within 4 hours of treatment and analyzed for dexamethasone
This is an inherent disadvantage with the passive absorption technique
154 showed that the absorption of the negative ion I 131 through unbroken skin only occurred in those conditions which included iontophoresis
6 There was no measurable reduction in collagen deposition (an effect of corticosteroids) in the The results of human experiments suggest that current magnitude and duration should be considered as factors in treating musculoskeletal dysfunctions with iontophoresis using DEX/DEX-P at a concentration of 4 mg/mL
9%), or a solution containing an anticholinergic medication, which allows ionised (charged) particles to cross the normal skin barrier
On the top is the oval delivery electrode which has the dexamethasone reservoir directly below the clamp
Erickson, J
Iontophoresis and Localized Drug Retention
Wascher, 2008 Skip to main content Iontophoresis is a type of electrical stimulation used in physical therapy
5 mg, 0
Dexamethasone, a synthetic adrenocortical steroid, is a white to practically white, odorless, crystalline powder
Methods: This article reviews available data on recent clinical applications of iontophoretic ophthalmic drug delivery
Turner J, Belch JJ, Khan F
L
If you use a unit at home, be sure to follow the instructions that come with the machine