In a small study involving patients with pleural effusions and refractory
While this treatment will not help those who have reached kidney failure and are
2 days
Amazingly, the most commonly used agent, talc, was first introduced as far back as 1935 []
1% of patients had successful pleurodesis, 18
Indication
Similarly, talc was completely or partially effective in 659 patients (91%) among 723 patients in 32 serial
752 out of 1,168 patients
In both groups, chest pain was the most common complication
We evaluated the utility of a single 1-g dose of doxycycline in the treatment of malignant and nonmalignant pleural effusions and refractory pneumothoraces in 27 consecutive patients requiring pleu Skip to Article Content; Skip to Article Information; Search In the only randomised and controlled study to date, Putnam and colleagues145 compared a long-term indwelling pleural catheter with doxycycline pleurodesis via a standard intercostal tube
7% of cases and partial in 10% of cases; however, failure was observed in 14
With the exclusion of the 6 patients who had short-term failure of
Preparation: 500 mg of Doxycycline is mixed with 25 mL of fluid (combination of sterile water and 1%Lidocaine) and 25 mL of contrast; Sequential sample of 12 pediatric patients who underwent cardiotomy for congenital heart disease and received doxycycline pleurodesis for persistent pleural effusion that lasted more than 7 days between December 21, 2001, and May 23, 2005
In this issue of Chest (see page 1162 ), Milanez and colleagues describe their experience with thoracoscopic management of spontaneous pneumothorax
A Cochrane review reported that pleurodesis with talc is superior when compared with other sclerotic agents (Table 1) or chest drainage alone to control an MPE or prevent the re-accumulation of fluid in the pleural cavity
Small studies of other agents like doxycycline have reported recurrence rates of 13-35% [3]