The risk for cataract was higher among statin users in comparison with nonusers in the propensity score–matched cohort (odds
29, 95% CI 1
Introduction
Statins [3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA) inhibitors] are recommended as the treatment of first choice for management of
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Mechanism of Action Statins are a potent drug for lowering low-density lipoprotein (LDL) cholesterol in the treatment of hypercholesterolemia and mixed
Even before
1, 2 Any common exposure that increases the risk of cataract is therefore of great public health importance
” Long-term administration of simvastatin and other statins (eg, lovastatin and fluvastatin) has been associated with cataract development in dogs, 5,6 while atorvastatin and pravastatin lacked a cataractogenic effect in dogs
Rhabdomyolysis can cause extreme muscle pain, liver damage, kidney failure and death
Common Zocor side effects may include: headache; constipation, nausea, stomach pain; or
Increased disproportionality for cataract and statins (drug-class) have been found regardless of statin lipophilicity, sex and group age (more or less than 65 years old)
To investigate whether the statin class of drugs reduces the risk of cataract extraction
Drugs that lower your cholesterol can be risky when combined with other meds
This is not a complete list of side effects and others may occur
The label on your medicine bottle will tell you if you need to take your statin at a certain time of day and if you need to take it with food
In many cases, these interactions can increase the risk of muscle pain and damage
Why statins increase risk of cataracts is largely unknown, but the researchers said the drugs could affect the outer cortical region of the eye where cholesterol biosynthesis occurs to keep lenses clear and structurally sound
Statins are drugs that can lower your cholesterol
Similar trends were observed in sensitivity analyses (except for fibrates and nicotinic acid after exclusion of reports with at least two LLD or in older patients ≥75 years)