Valacyclovir 1 g orally once a day
, ≥10 episodes/year) Data were collected on the number of HSK episodes before and after the diagnosis of resistance, ocular findings including the type of HSK, immune status of patients, antiviral treatments and HSV-1 genotypic resistance profiles
See more Typical drugs from these three categories include valacyclovir (VCV)
The frequency of genital HSV-2 acquisition increased with the reported
Acyclovir resistance amongst immunocompetent patients with HSV keratitis can be as
It can also cause infection in the eye, skin, central nervous system, and/or visceral organs
Dis
All acyclovir-resistant HSV strains are resistant to valacyclovir, and it is very rare that they are sensitive to famciclovir
, Hofmann W
In the world of antiviral medications, two commonly prescribed drugs for the treatment of herpes infections stand out: Acyclovir and Valtrex
Valacyclovir and acyclovir work to lessen pain and expedite the healing of sores or blisters in people with chickenpox, shingles (also known as herpes zoster ), genital herpes (in adults), and cold sores (also known as herpes labialis)
The antivirals ( oral, intravenous and topical) acyclovir, valacyclovir, famciclovir and pensiclovir are well established treatments for both HSV-1 and HSV-2
Second-line therapies recommended for acyclovir-resistant HSV infections include foscarnet and cidofovir
Herpes simplex viruses are among the most ubiquitous of human infections
2003; 163:76–80
3% in immunocompetent patients [19, 20]
Berger, MD, Department of Neurology, University of Kentucky College of Medicine, Kentucky Clinic Room L-445, 740 S Limestone St, Lexington, KY
Therapy was most effective when administered within 48 hours of the onset of signs and symptoms
15,16,23,24 One patient’s vulvar lesions resolved after 21 days of acyclovir treatment, while other patients’ vulvar lesions were unresponsive to high doses of oral acyclovir and/or valacyclovir
, and 1 man aged 42 yrs