Basically, my hypothesis is that mirtazapine reduces/negates the euphoric properties of opiates/opioids, due to κ-opioid agonism
Venlafaxine is an antidepressant that may also be used for mood disorders and off-label for some other conditions such as hot
Summing up the various interactions of venlafaxine and mirtazapine with opioid, noradrenergic and serotonergic agonists and antagonists, we found that the antinociceptive effect of venlafaxine is influenced by opioid receptor subtypes (mu-, kappa1- kappa3-
We propose an alternative single medication, mirtazapine, a noradrenergic and specific serotonergic receptor antagonist, that can be used for myriad symptoms of
Summing up the various interactions of venlafaxine and mirtazapine with opioid, noradrenergic and serotonergic agonists and antagonists, we found that the