Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma
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Background
Acetazolamide is used to prevent and reduce the symptoms of altitude sickness
Acetazolamide is a carbonic anhydrase (CA) inhibitor sometimes used as a respiratory stimulant for patients with chronic obstructive pulmonary disease (COPD) with the goal of improving oxygenation, reducing carbon dioxide retention, and aiding liberation from mechanical ventilation and/or attempting
Comments: Therapy should be initiated 24 to 48 hours before ascent and continued for 48 hours while at high altitude, or longer as necessary to control symptoms
Drug information provided by: Merative, Micromedex
The adult dose is 4 mg every 6 hours; rarely is it needed for more than 1–2 days
The use of acetazolamide or placebo was stopped at the discretion of the physician because of hypotension (in 4 and 2 patients, respectively) or an increase in the serum creatinine level (in 1 Acetazolamide 250mg Tablets are used to treat: glaucoma (a condition of the eye), by reducing the pressure within the eye
This medicine is also used to treat seizures (eg, petit mal, unlocalized seizures)
For best results, put one drop 2-3 times daily in the affected eye (s)
unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
It is also used to treat open-angle glaucoma, secondary glaucoma, and acute angle-closure glaucoma before surgery to lower pressure inside the eye
Prior reviews focused on specific subtypes of sleep apnea, study designs, and languages, thus including few studies (typically ≤3) limiting insights Acetazolamide is the only carbonic anhydrase inhibitor with significant diuretic effects
Acetazolamide can work less well over time, so it is usually used only for a short period
The adverse effects of CAIs that researchers and patients have reported include fatigue, vomiting, nausea, and abdominal pain