15 A more recent study evaluated the use of extended-release divalproex compared with placebo in 239 patients
Topiramate is freely soluble in polar organic solvents such as acetonitrile and acetone; and very slightly soluble to practically insoluble in non-polar
13 TPM-IR dosed twice daily is characterized by a plasma elimination half-life that ranges from 21 to 42 h and dose proportional
Based upon tolerability, the dosage can be increased to 50 mg/day in the second week
75 mg-23 mg; 7
2
Patients with commercial insurance coverage are eligible to receive $65 off 3
Trokendi XR is taken once a day, while Topamax is usually taken twice a day, in the morning and evening
Do not take two doses at one time
Based upon tolerability, the dosage can be increased to 50 mg/day (25 mg twice daily) in the second week
5 mg-topiramate 46 mg: Weight loss should be evaluated; if less than 3% of baseline body weight has been lost, the dosage should be increased
This Learn about the indications, dosage, warnings, and precautions of Trokendi XR, a once-daily extended-release formulation of topiramate for the treatment of epilepsy and migraine