The 10-mg dose provides elevated corticosteroid levels above baseline for five to seven days and provides a physiologic taper by drug metabolism,lo Our sample size was too small to evaluate a dose response curve based on patient weight
No side effects and no new complaints attributable to the dexamethasone and azithromycin were observed
Whereas antibiotics have no analgesic activity, a single low dose of a corticosteroid such as oral dexamethasone—0
The treatment variable consisted of a 10 mg IM dose of dexamethasone or saline placebo
According to the reports of this study, children with GABHS pharyngitis who received oral dexamethasone as add-on therapy had a more rapid improvement in
Dexamethasone 10 mg IM (10 mg/mL) (31 participants) or 1 mL saline IM (27 participants)
Main Outcomes and Measures Primary: proportion of participants experiencing
It works on the immune system to help relieve swelling, redness, itching, and allergic reactions
02 to 0
A prospective, randomized, double-blinded, placebo-controlled clinical trial was undertaken over a 3-month period in a university-based Emergency Department
3; risk difference 12
used 10 mg steroid in pain relief in children with positive antigen detection their study, although the appropriate steroid dose is not than in all children with acute pharyngitis treated with known for exudative pharyngitis (4,17)
6 to 9 mg/m 2 bsa/day)
05) faster onset of pain relief and shorter suffering, especially in children with severe or exudative group A β-hemolytic streptococcus-positive acute pharyngitis
INTERVENTIONS: All patients received oral penicillin (500 mg Pen VK) or erythromycin (333 mg base) three times daily for ten days in addition to either 10 mg single-dose dexamethasone or saline placebo IM injection
In patients with severe, acute exudative pharyngitis, single-injection dexamethasone adjuvant compared with placebo resulted in statistically Answer A single dose of oral dexamethasone (0
6 mg/kg with a maximum of 10 mg) or placebo of the same volume
Children—Dose is based on body weight and must be determined by your doctor
In the present study we only measured VAS score on presentation
The short-lived relief of pain in acute exudative pharyngitis in children with suspected infectious mononucleosis may suggest that a single oral dose of dexamethasone may not be sufficient and that additional doses may be necessary for ensuring lasting relief
This medicine is available
To examine the efficacy of a single dose of oral dexamethasone (0
In 1 study, a second intervention arm received dexamethasone for 3 days
25, 0
02; effect size of 5
e
Main Outcomes and Measures Primary: proportion of participants experiencing complete resolution Betamethasone (Celestone) 0
5-10 mg/day PO/IM/IV divided every 6-12 hours