0 nM), was administered by a slow-drive syringe pump into the artificial plasma
Low plasma concentrations of dexamethasone primarily act on the anterior pituitary to suppress pituitary-adrenal secretion
Numerous mRNAs regulated by dexamethasone were also regulated by the natural ligand corticosterone; all of the mRNAs regulated ≥twofold by corticosterone
Human mineralocorticoid receptors have equivalent high affinity for cortisol, corticosterone, DOC, progesterone and aldosterone
Even though
Corticosteroids work by causing metabolic effects and modifying the body’s immune response to stimuli
The expressions of NeuroD, BDNF, and NR1 mRNA levels and protein levels of p-ERK and p-CREB were remarkably decreased by corticosterone in a dose
A General Introduction to Glucocorticoid Biology
Correlation between Serum and Ocular Corticosterone and Dexamethasone Levels
04, n = 8]
Moreover, in a 100-fold excess, it does not compete in vivo for retention of corticosterone in hippocampus ( 23 )
L929 fibroblasts grown in DMEM/10 per cent bovine calf serum were homogenized in HEM buffer (10 mM Hepes Induction of liver glycogen deposition in adrenalectomized rats by corticosterone, dexamethasone and 11-deoxycorticosterone, 100 µg per 100 g
0 n m) was administered by a slow-drive syringe pump into the artificial
Dexamethasone and its derivatives are almost pure glucocorticoids, Aldosterone and corticosterone share the first part of their biosynthetic pathway
To activate both low-affinity GRs and high-affinity MRs fully, we used the high concentration of 100 n M corticosterone, as used in other in vitro studies of the corticosteroid stress hormone Dexamethasone vs
Downstream, this affects the production of mRNA and subsequent protein synthesis
Given the 10-fold difference in Corticosterone and dexamethasone additively enhanced the expression of Fkbp5 and Mt2a in liver, and of Mt2a in iBAT and
1
Systemic corticosteroid therapy is widely used for various inflammatory and autoimmune conditions, but it also carries significant risks of complications
Glucocorticoids also antagonize TCR signaling and alter the threshold of TCR affinity for self peptide:MHC that results in survival and proliferation vs
Dexamethasone is an effective and well-tolerated component of antiemetic combination therapy
Cortisone and hydrocortisone are both corticosteroids (often shortened to "steroids")