See more Propafenone and flecainide have the slowest dissociation kinetics of the sodium channel blocking drugs and therefore have more bound drug and produce a greater degree of
A combination of two drugs (eg, propafenone and amiodarone, sotalol and propafenone) may be required in some cases
Using propafenone together with amiodarone can increase the risk of an irregular heart
Drug interactions with dabigatran, occurring as a result of P-gp inhibition and producing elevated dabigatran levels, could be anticipated with use of the following
The arrhythmia recurred in 54 (52%) patients treated with propafenone and in 80 (76%) with amiodarone, p < 0
Propafenone versus amiodarone for supraventricular arrhythmias in septic shock: a randomised controlled trial Original Published: 12 September 2023 Volume 49
electrolyte
In conclusion, in this population of AF patients with previous amiodarone loading, immediate switch appears to be a convenient and effective option
Drug interaction information
Both amiodarone and propafenone are available interventions, but their clinical effects have not yet been directly compared
Check with your doctor immediately if any of the following side effects occur while taking propafenone: Less common
AIMS Mixed treatment comparisons (MTC) were performed to assess the relative efficacy and tolerability of the main anti
previous studies have shown that a combination of amiodarone and digoxin is associated with high all-cause mortality compared to
Increasing age, female sex, cardiac disease, and some metabolic disturbances (notably hypokalaemia) predispose to QT prolongation
Am J Cardiol 1999;84: 1029-1032
12 In the AFFIRM (Atrial A combination of two drugs (eg, propafenone and amiodarone, sotalol and propafenone) may be required in some cases
If you've tried several times to cardiovert with pharmacologic/DCC options and the patient is still symptomatic, it's time to consider catheter ablation
To judge the efficacy and safety of this combination, we reviewed the case notes and results of investigation in all nine children with supraventricular tachycardia who received such therapy between 1984 and 1993
Toxicity tends to occur when the serum colchicine concentration exceeds 3
The SAFE-T trial, the only randomized double-blind study of amiodarone, randomized AF patients to either placebo ( n = 137 patients), sotalol ( n = 261 patients), or
Even combination of BB with propafenone and flecainide did not show superior efficacy in comparation with individual antiarrhythmic drug treatment without BB
Both drugs were administered in a combination of intravenous and oral doses