Generic name: ezetimibe [ ez-ET-i-mibe ] Drug class: Cholesterol absorption inhibitors Medically reviewed by Sanjai Sinha, MD
If you have kidney problems and you’re taking Zetia with a statin, you have an increased risk of muscle problems
6% in men and 7
How it works Zetia is a brand (trade) name for ezetimibe which may be used to lower high cholesterol
This medicine will reduce the absorption of cholesterol from foods and the production of cholesterol in your body
Call your doctor right away if you have unexplained muscle pain
Muscle problems are more commonly linked to statins
The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (study of heart and eenal protection): a randomised placebo-controlled trial
To obtain a greater effect, ezetimibe may be given with a statin
A subset of six patients with urinary oxalate values both on and off ezetimibe showed a difference in 24-h urinary oxalate levels ranged from -16 With respect to safety, the SHARP trial showed that ezetimibe 10 mg plus simvastatin 20 mg can be safely used in individuals with moderate to severe reductions in kidney function
light-colored stools
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
Ezetimibe in Chronic Kidney Disease (CKD) Individuals with CKD are at heightened risk for cardiovascular mortality, and eGFR is an independent and robust predictor of risk
It is also used to treat a condition called homozygous familial For example, the risk of CIN in people with advanced CKD (glomerular filtration rate ( GFR) below 30 mL/min/1
muscle pain while taking ezetimibe with a statin
The kidneys of older adults may Ezetimibe is a second-line lipid-lowering agent that reduces sterol absorption, and has a favorable effect on lipid profile
For exact diagnosis, you are requested to consult your doctor
These may be symptoms of myopathy or rhabdomyolysis, which may lead to muscle breakdown and kidney damage
Other serious side effects include muscle tenderness or weakness, chest pain, nausea In Zetia’s clinical studies, these were some of the side effects that occurred more often: pain in the arms or legs
* For more information about this side effect, see “ Zetia: Side effects explained ” below
Changes to diet and exercise are often combined with this medication
These medicines will reduce the absorption of cholesterol from foods and the production of cholesterol in your body