Probenecid inhibits tubular secretion

Probenecid inhibits the tubular secretion of thiazides by interfering with their transport via OATs, consequently reducing delivery of thiazides to the lumen of. Probenecid inhibited the renal tubular secretion of ciprofloxacin and M1, probably by a competitive mechanism and due to reaching >100-fold higher plasma

2024-03-28
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  1. Aspirin In low dosages (up to 2
  2. Probenecid is a uricosuric and renal tubular blocking agent