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Metronidazole doses are usually decreased 50% in patients with significant liver disease; tinidazole has not been studied in liver disease and should be used with caution if at all
Tinidazole is used to treat infections caused by protozoa (eg, trichomoniasis, giardiasis, and amebiasis)
Tinidazole is superior to metronidazole with regard to efficacy and tolerability
Secnidazole had cure rate of 80
Tinidazole and ornidazole are recently developed nitroimidazole derivatives that have even greater antimicrobial activity than metronidazole
Metronidazole and tinidazole can interfere with alcohol metabolism and can cause unpleasant side effects similar to those of a hangover including nausea, vomiting
Tinidazole is taken by mouth