Reproduction studies performed in rats at a dose of 3 mg/kg, equal to the maximum recommended human dose on a mg/m2 basis, and in rabbits at 30 mg/kg, 16 times the maximum recommended human dose on a mg/m2 basis, did not show evidence of tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding
Pediatric Use
dosimetry or therapeutic iobenguane I 131 infusion; avoid combo during and for at least 7 days after iobenguane I 131: combo may decr
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48% of reviewers reported a positive effect, while 30% reported a negative effect
Tizanidine hasn’t been adequately studied in pregnant women
That means two things: Research in animals has shown adverse effects to the fetus when the
Takeaway
Tizanidine Baclofen Amitriptyline Onabotulinum toxinA Category A: Safety studies in pregnant women show no harm
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Breastfeeding
Oral administration of tizanidine (1 to 100 mg/kg/day) to pregnant rabbits during the period of organogenesis resulted in embryofetal and postnatal offspring
This sheet is about exposure to baclofen in pregnancy and while breastfeeding
Tizanidine withdrawal is a rare condition characterized by a sudden surge in adrenergic activity, leading to symptoms such as tachycardia, rebound hypertension
However, because it is lipid-soluble, tizanidine might be expected
When a pregnant woman does get a migraine, there are as-needed medications that are considered likely to be safe
Tizanidine (Zanaflex) isn't a controlled substance, so it isn't known to cause an
There was 1 report of malformations (aortic arch coarctation, cardiac enlargement, cutaneous edema) in animal models given IV doses of 20 mg/kg, and 1 report of lightheadedness, dizziness, or fainting
slow or irregular heartbeat
However, when these medicines are used at higher doses and/or for a long time, the chance that problems might occur may increase
Reproduction studies performed in rats at a dose of 3 mg/kg, equal to the maximum recommended human dose on a mg/m 2 basis, and in rabbits at 30 mg/kg, 16 times the
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Alprazolam
Oral administration of tizanidine (1 to 100 mg/kg/day) to pregnant rabbits during the period of organogenesis resulted in embryofetal and postnatal offspring mortality at all doses
Tell your doctor if you are pregnant or plan to become pregnant
Tizanidine should be given to pregnant women only if the benefit outweighs the risk to the unborn fetus
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It can be prescribed for short-term or long-term use, depending on your Oral administration of tizanidine (1 to 100 mg/kg/day) to pregnant rabbits during the period of organogenesis resulted in embryofetal and postnatal offspring mortality at all doses
Common side effects of tizanidine include dry mouth, sleepiness, weakness, and dizziness
Tizanidine has an average rating of 6
Driving and using machines Tizanidine may cause drowsiness or dizziness (see section 4)
Of the total drug interactions, 237 are major, 365 are moderate, and 2 are minor