Poor bioavailability of acyclovir

In fact, nanoparticles do offer many advantages, especially in terms of their Abstract. Since premature hydrolysis of this prodrug in the intestinal lumen may be a possible reason for its incomplete bioavailability and the chemical and enzymatic stability of the valacyclovir has been investigated

2024-03-28
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  1. Valacyclovir is the L-valyl ester of acyclovir
  2. Acyclovir has poor bioavailability, which is about 10 to 20%
  3. The intention of this research work was to formulate and
  4. 5%
  5. 30 – 2
  6. 27 and 9
  7. 0 +/- 0
  8. 1±0
  9. The interindividual variations of the bioavailability were 48
  10. 5 h) (Chiou and Barve, 1998)