Chemically modified tetracyclines

Jun 12, 2012 · Tetracyclines (TCs) are a class of antibiotics able to inhibit protein synthesis in gram positive and gram negative bacteria by preventing the attachment of aminoacyl-tRNA to the ribosomal acceptor (A) site [ 2 ]. Due to chemical modification, CMT lacks the antimicrobial activity, due to which chances of development of antibiotic resistant microbial flora diminishes in long-term therapy

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  1. The CMTs are designed to be Abstract
  2. T Figure 5
  3. 2005 Nov;73(11):7548-57