In the present review, we first summarize the clinical use and unique pharmacology of amiodarone
Amiodarone is an antiarrhythmic agent commonly used to treat supraventricular and ventricular arrhythmias
Amiodarone is an anti-arrhythmic drug widely used, but its administration can be associated with several adverse side-effects
Amiodarone-Induced Pulmonary Toxicity—A Fatal Case Report and Literature Review Felix T
The incidence of
The major adverse reaction associated with use of this drug is a life-threatening pulmonary toxicity, which develops in a substantial percentage of patients
Therefore, vigilant monitoring is advised
Med
The most fatal manifestation of pulmonary toxicity is a rapidly progressing diffuse pneumonitis with acute respiratory distress requiring mechanical ventilation with mortality as high as 50 to 100% Amiodarone is a widely used and very potent antiarrhythmic substance
One of the more serious adverse effects includes amiodarone pulmonary toxicity (APT)
The case of a 63-year-old male with classic radiographic and histologic findings of APT is discussed
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This review provides an update of the epidemiology
Amiodarone, a potent antiarrhythmic, is known to cause pulmonary toxicity
This case is unique for two reasons
As displayed in Figure 1, pulmonary toxicity was the third most common adverse reaction, with 116
Among the most severe adverse events include a spectrum of amiodarone-induced pulmonary toxicity (AIPT)
Toxicity is related to cumulative dose and typically occurs after at least two months on
Methods: A nationwide population-based study was conducted among patients with incident atrial fibrillation (AF) between 1 December 1999 and 31 December 31 2021
Of these events, the most serious is amiodarone pulmonary