Hydroxychloroquine is a prescription drug used to treat many autoimmune disorders
The study found no significant difference in standardised cumulative COVID-19 mortality associated with hydroxychloroquine use (0·23% among hydroxychloroquine users and 0·22% among non-users) with an adjusted hazard ratio of 1·03 (95% CI 0·80–1·33)
We now know that high-dose hydroxychloroquine is not life-saving in late disease, nor indeed is any antiviral to date, whereas dexamethasone significantly reduces mortality
Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective
Using this medicine alone or with other medicines (eg, azithromycin) may
Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors within the first month after the start of treatment
How do you take Plaquenil? You take Plaquenil as a pill 1 or 2 times a day
From May 12, 2020 to July 07, 2021, 1372 patients were randomly allocated to hydroxychloroquine or placebo
Hydroxychloroquine was found could potentially induce or intensify AKI by increasing lysosomal pH and inhibiting autophagy, because it has been demonstrated that Hydroxychloroquine inhibits autophagic flux by impairing autophagosome-lysosome fusion
This review describes the history, mechanisms, pharmacokinetics, therapeutic applications, and safety profile of hydroxychloroquine as an immunomodulatory and antiviral agent
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Hydroxychloroquine is one of the most frequently used drugs in dermatology with a wide variety of uses due to its immunomodulatory, anti-inflammatory, photoprotective, and metabolic actions and low side effect profile
Today, increased Plasmodium resistance has limited its use to a few specific geographic regions
It has also been used to treat COVID-19, Q fever, and Sjögren’s syndrome