Includes newsletter, church bulletin, message from the pastor, and worship schedule
Increasing antimalarial drug resistance once again threatens effective antimalarial drug treatment, malaria control, and elimination
1 Successively, these parasites have acquired resistance to chloroquine, sulphadoxine-pyrimethamine, mefloquine, and more recently the artemisinins through
Accelerated elimination of all falciparum malaria in the Greater Mekong subregion will be needed to counter the threat of artemisinin and Background The rise in Plasmodium falciparum resistance to dihydroartemisinin–piperaquine (DHA–PPQ) treatment has been documented in the Greater Mekong Subregion with associations with INTRODUCTION
History shows that chloroquine resistance had arisen from this region in the 1950s Mayxay M, Rekol H, et al
The emergence and spread of fit artemisinin-resistant P falciparum parasite lineages, which then acquire
Economic corridors of the Greater Mekong Subregion Mekong River sunrise, Phnom Penh, Cambodia
The identification of molecular markers makes surveillance of parasite genotypes an important supplement to monitoring of the parasite response to different treatments
A single long pfkelch Cys580Tyr haplotype (from −50 kb to +31·5 kb) conferring artemisinin resistance (PfPailin) now dominates across the eastern Greater Mekong subregion
To characterise resistance emergence, a treatment efficacy study was performed on the reported patients infected with P falciparum and treated with dihydroartemisinin–piperaquine in French Guiana (n=6, 2016–18)
In the Greater Mekong subregion (GMS), artemisinin resistance is increasingly compounded by partner drug resistance, causing high failure rates of artemisinin combination therapies in some areas
Most countries in Southeast Asia are making steady progress in reducing the malaria burden; the six countries in the Greater Mekong Subregion (GMS) have set their goals
Southeast Asia, and particularly the Greater Mekong Subregion (GMS), has historically been the epicenter for development of antimalarial drug resistance phenomena
1998; Background Plasmodium vivax is the most widely distributed malaria parasite, and its drug resistance poses unique challenges to malaria elimination