)
For a typical study neonate with HIE receiving hypothermia, theophylline clearance was 14
Theophylline
Intravenous preparations of aminophylline contain from 75 to 85% theophylline by weight
Pharmacological Effects The pharmacological effects of theophylline are very similar to those of caffeine
The availability of sustained-release theophylline preparations has already proved to be an advance in asthma pharmacotherapy
The pharmacokinetics of theophylline were investigated in 13 infants, 4
Presented at the American College of Allergists (San Francisco, April 1976)
3%, p < 0
7 59,1 pharmacokinetics was therefore' tested in both 4 4 16 24
s001
The clearance of theophylline decreases by about
Theophylline is metabolized by the liver with plasma clearance that can be effected by liver disease, cigarette smoking, or by changes in diet
In Part 2 the clinical pharmacology of three commonly used drugs (theophylline, digoxin and examine the pharmacokinetics of theophylline
Aminophylline (200 mg) was administered every The pharmacokinetics of theophylline were investigated in 13 infants, 4 to 18 months of age
5 min, respectively
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Routine clinical pharmacokinetic data collected prospectively from pediatric patients receiving theophylline were analyzed using the NONMEM (nonlinear mixed effects model) digital computer program