For example, high blood pressure, diabetes, and related
and kidney function found atorvastatin (ATV) protective and rosuvastatin (RSV) nonprotective or possibly harmful in dia-betic or nondiabetic patients
Healthcare professionals should offer statins to millions of people with chronic kidney disease (CKD)
49 Our group
Introduction
Statins are widely prescribed medications used to lower cholesterol levels and reduce the risk of cardiovascular diseases
End-stage renal disease hazard ratio for the combined endpoint in the rosuvastatin group vs
and kidney function found atorvastatin (ATV) protective and rosuvastatin (RSV) nonprotective or possibly harmful in dia-betic or nondiabetic patients
If you want to However, a 2014 meta-analysis 30 involving 6 RCTs compared high-intensity statin therapy (atorvastatin 80 mg or rosuvastatin 20 or 40 mg) with moderate-to-mild statin treatment or placebo and Multiple logistic regression analyses demonstrated more rapid renal function loss in the rosuvastatin group than in the atorvastatin group after adjustment for other confounding factors (odds atorvastatin ; rosuvastatin pravastatin A 2018 review highlights some observational studies that suggest statins may help to protect the kidneys following major noncardiac surgery
6 for hematuria, 3
Statins Atorvastatin (Lipitor) Fluvastatin (Lescol XL) Lovastatin (Altoprev) Pitavastatin (Livalo) Pravastatin (Pravachol) Rosuvastatin (Crestor) Simvastatin (Zocor) Decrease LDL and triglycerides; slightly increase HDL
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However, in the Bayesian network meta-analysis, compared to the placebo, only atorvastatin 80 mg daily and atorvastatin and rosuvastatin at doses equivalent to simvastatin 20 mg daily reduced the Similar effects of rosuvastatin and atorvastatin
The recommended dose in adults is 5 to 40 mg once daily, based upon tolerability and lipid levels
The FDA-approved indications are homozygous familial hypercholesterolemia, hyperlipidemia, mixed dyslipidemia, primary dysbetalipoproteinemia, hypertriglyceridemia, and prevention of cardiovascular disease
These medications have also been linked to a lower risk of heart disease and stroke