The generic version of the drug, alendronate, comes in two forms: an oral tablet and an oral solution
FAQ What is Fosamax? Fosamax is a bisphosphonate (bis FOS fo nayt) medicine that alters bone formation and breakdown in the body
Individuals with untreated calcium deficiency or esophageal disease should not use this treatment
Merck & Co
bone with osteoporosis The most common side effects of Fosamax during clinical trials included abdominal pain, nausea, acid regurgitation, indigestion, constipation, diarrhea and musculoskeletal pain
It works by slowing the breakdown of bones so that the body has a chance to build up more bone; this strengthens bones and lowers the risk of fractures
Chandrasekaran, MD If you have osteoporosis (weak, brittle bones), then you may have heard some negative stories about the osteoporosis medication Fosamax
Bisphosphonates are less expensive than the alternatives, are safe in the long term, and are effective in preventing fractures
Fosamax can be dosed once daily or once weekly for treating osteoporosis
a T-score of -2
My memory improved, my bone pain resolved, foot pain Drug information provided by: Merative, Micromedex® US Brand Name
A bisphosphonate drug holiday allows time for the medicine to be removed from the bone and reestablishes the normal bone remodeling cycle
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Alendronate is used to prevent and treat osteoporosis (thinning of the bone) in women after menopause
First, old bone is removed (resorbed)
Indicated for treatment and prevention of osteoporosis in postmenopausal women
Binosto: 70 mg PO once weekly
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39% of reviewers reported a positive effect, while 39% reported a negative effect
Measure liquid doses carefully
Moderate risk of fracture: treat with bisphosphonate for 5-10 years, offer a 'drug holiday' of 3-5 years or until there is significant loss of BMD or the patient has a fracture, whichever comes first
Although better nutrition, increased physical activity, and education on fall prevention may have played a role, the drop in fractures has also coincided with the widespread availability of bisphosphonates—a class of drugs first approved in 1995 to increase bone density
You should store Fosamax tablets at room temperature, between 59°F and 86°F (15°C and 30°C)
6 out of 10 from a total of 74 reviews on Drugs
In order to help prevent gastrointestinal distress, the nurse will advise the patient to Medications can markedly reduce fracture risk
Number one, they are both antiresorptive, osteoclast inhibitors An "average" 80-year-old woman would have a FRAX result of greater than 20% risk of major osteoporotic fracture
c-"I need to sit or stand upright for at least 30 minutes Alendronate is approved by the U
The risk is real, but rare
These effects on bone homeostasis can temporarily increase bone mineral density but eventually produce old, weak bones
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Evista (raloxifene) Parathyroid hormone/parathyroid hormone-related protein analogs
They advise that women whose risk is still high should continue to take oral bisphosphonates for up to 10 years or IV therapy for up Bisphosphonates are widely prescribed for osteoporosis; more than 150 million prescriptions were dispensed to outpatients between 2005 and 2009
It works by slowing the breakdown of bones so that the body has a chance to build up more bone; this strengthens bones and lowers the risk of fractures
increased blood pressure
It helps to preserve or maintain bone density during menopause — and decrease the risk of breaking a bone as a result of osteoporosis
4 percent
Fosamax has an average rating of 2
Fosamax is a brand (trade) name for alendronate which may be used for the
treat osteoporosis in males* treat osteoporosis that’s caused by taking
Overview Fosamax (alendronate) is a brand-name prescription medication
Any thoughts on what might be best? ANSWER: Oral bisphosphonate
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The Food and Drug Administration greenlighted a new drug on Friday that
) Fosamax works to decrease bone
Other beverages (including mineral water), food, and some medications are likely to reduce the absorption
Measure liquid doses carefully
It is common in women after Fosamax: 10 mg PO qDay or 70 mg (tablet and oral solution) once weekly; Binosto: 70 mg PO once weekly; Glucocorticoid-Induced Osteoporosis
This is because the brand-name form of the drug only For treating or preventing osteoporosis, clinical studies of Fosamax only looked at the drug when used for up to 4 years
I am a 63-year-old female who recently had my first bone density scan
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Abstract
Fewer people have used risedronate and ibandronate, primarily because they have not been available as long as alendronate
FDA warnings apply to: Fosamax
Protein is estimated that approximately 40% of 50-year-old women will sustain one or more osteoporosis-related fractures of the spine Studies of long-term use of bisphosphonates
Opponents of a drug holiday argue that, given the long half-life of bisphosphonates (i
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Allegations against the drug company include failure to warn and manufacturing a defective drug
1995: The FDA approves Fosamax ( alendronate sodium) oral tablets, manufactured by Merck