38% of reviewers reported a positive effect, while 51% reported a negative effect
The conversion rates were the lowest in persistent AF studies [ 8, 10] ranging between 19 and 24% for sotalol and 26 and 27% for amiodarone, while in recent onset
Compared with those treated with amiodarone or no AAD, patients treated with sotalol were less likely to be black (6% vs 13% vs 13%) and have a previous
The availability of intravenous (IV) Sotalol has equalized the treatment options since both amiodarone and sotalol are available in both IV and oral
6,7 The efficacy of the ICD for terminating ventricular tachyarrhythmias is contingent on
Sotalol is superior to amiodarone for long-term treatment of ventricular tachyarrhythmia secondary to coronary artery disease when both drugs have been
45 compared with -blocker group and P 0
Abstract Background Atrial tachyarrhythmias are common after atrial fibrillation ablation, so adjunctive antiarrhythmic drug therapy is often used
15 Apart from efficacy data, there are relatively few data on the But amiodarone was nearly six times more effective in maintaining SR with prolonged time to recurrent AF (487 vs
Objective: The purpose of this study was to evaluate the safety and efficacy of IV sotalol for postoperative JET and compare outcomes with IV amiodarone
Sustained sinus rhythm is associated with an improved quality of Specific interventions included in the review
The cohort was restricted to patients who received a prescription for isolated dronedarone or amiodarone antiarrhythmic therapy within 2 days of discharge, thereby avoiding any potential immortal time bias
1, 3–6 Based on these data, these drugs have been recommended by the guidelines for use in the CHD population
The poor quality of many of the
Six antiarrhythmic drugs are often used to treat atrial fibrillation: propafenone (Rhythmol), flecainide (Tambocor), sotalol (Betapace), dofetilide (Tikosyn), amiodarone (Cordarone), and dronedarone (Multaq)
Digoxin should be avoided Several studies have shown that sotalol and amiodarone are both effective in reducing AFF following heart surgery
a Odds ratios are reporting amiodarone vs
Sotalol is indicated in premature ventricular contractions
Aim: To compare the efficacy of sotalol versus amiodarone for long-term treatment of ventricular tachyarrhythmias
Amiodarone had the largest effect in reducing AF recurrence (OR 0
In a randomized placebo‐controlled trial comparing sotalol, amiodarone plus metoprolol, metoprolol, and placebo for prevention of AF after cardiac surgery, sotalol had similar efficacy to amiodarone plus metoprolol (both better than placebo) for suppression of AF, but had a 3‐fold higher risk of bradycardia requiring dose reduction and/or Drug interactions
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OBJECTIVE—To assess and compare the safety and efficacy of amiodarone and sotalol in the treatment of patients with recurrent symptomatic atrial fibrillation
Sotalol was originally approved by the FDA (tradename Betapace) for the treatment of life-threatening ventricular arrhythmias