If any of these effects last or get worse, tell your Pain or trouble swallowing
Jun 27, 2023 · Side effects of olanzapine include: Dizziness/ low blood pressure upon standing
Extrapyramidal symptoms (EPS), dose dependent (muscle spasms, jerky movements, slow movements) Dry mouth
It also enhances appetite and may cause weight gain when used for the maintenance of
A dose of ~100 mg PO q8hr has been utilized as the primary sedative for intubated patients, up to a maximal dose of ~400 mg/day
5 -5 m g, max 30 m g/24
When the IM olanzapine finally reaches peak effect, the combination of olanzapine plus several doses of benzodiazepine could cause over-sedation (“dose
Dosage Forms Pharmacology Pharmacokinetics Specific Populations Use: Labeled Indications Use: Off Label Contraindications Dosage Administration Dietary
Effects are long-lasting, so olanzapine should be dosed once a day; however, it may take several weeks of continued dosing before a reduction in symptoms is seen
Background and Objective: Olanzapine (OLZ) containing regimens are approved in adults for chemotherapy-induced nausea and vomiting (CINV) receiving
Patients & methods: A prospective, randomized, double-blind, controlled study was conducted, enrolling 68 patients receiving a single-day cycle of high and moderately emetogenic chemotherapy
Olanzapine may cause drowsiness, trouble with thinking, trouble with controlling body movements, or trouble with your vision, which may lead to falls, fractures or other injuries
The midazolam/droperidol group responded most rapidly, with no differences between the droperidol group vs
loss of bladder control
Post-Injection delirium/sedation syndrome, a collection of signs and symptoms consistent with olanzapine overdose has been reported following injections of the extended-release IM suspension
You can find detailed information about this drug in the official Patient Information Leaflet (PIL)
Adjusting the dosage or exploring alternative treatment options can help minimize these effects
The combination of olanzapine and samidorphan is also used to prevent episodes of mania in adults with bipolar disorder
, sedation) of the medication
For patients with ongoing pain this should be scheduled, to provide a baseline level of analgesia
Drowsiness, dizziness, lightheadedness, stomach upset, dry mouth, constipation, increased appetite, or weight gain may occur
Bipolar I (acute mixed or manic episode): Oral
Olanzapine administered at an initial dose of 5 mg IV or 10 mg IM appears to be a safe and effective choice for sedation of agitated ED patients
Olanzapine has a significant risk of hypotension and should be used with caution in patients with conditions that predispose to hypotension
Taking other sedative medications with olanzapine may result in added drowsy effects
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A severe and sometimes deadly reaction has happened
During clinical trials, a post-injection syndrome characterized by signs of delirium and/or excessive sedation was identified in a small percentage of patients following