It showed high affinity only for 5-HT but no affinity for other neurotransmitter receptors such as muscarinic, dopamine D1, D2, adrenergic alpha 1, alpha 2, and beta
Sumatriptan is approved by the U
Each IMITREX Tablet for oral administration contains 35, 70, or 140 mg of IMITREX (sumatriptan) injection, for subcutaneous use Initial U
SUMATRIPTAN INJECTION is not intended for the prophylactic therapy of migraine or for use in the management of hemiplegic, basilar, or ophthalmoplegic migraine (see CONTRAINDICATIONS)
2 Geriatrics Geriatrics (>65 years of age): Experience of the use of sumatriptan succinate in patients aged over 65 years is limited
On This Page Indications and Usage Dosage and Administration Dosage Forms and Strengths Contraindications Warnings and Precautions Adverse Reactions/Side Effects Drug Interactions subcutaneously 6 mg of sumatriptan (as the succinate salt) per 0
If you get some relief, or if the migraine comes back after being relieved, another dose may be taken 2 hours after the last dose
Sumatriptan succinate injection is not used to treat other types of headaches such as hemiplegic (that make you unable to move on APO-SUMATRIPTAN Page 1 of 40 PRODUCT MONOGRAPH INCLUDING PATIENT MEDICATION INFORMATION PrAPO-SUMATRIPTAN Sumatriptan Succinate Tablets tablet, 25 mg, 50 mg & 100 mg Sumatriptan (as sumatriptan succinate), oral Apotex Standard 5-HT 1 Receptor Agonist Migraine Therapy APOTEX INC
Chromatographic system (see Chromatography 621)— The liquid chromatograph is equipped with a 282-nm detector and a 4
It is taken orally, intranasally, or by subcutaneous injection
50-mg Tablets: White, triangular-shaped, film-coated, and debossed with "IMITREX 50" on one side and a chevron shape (^) on the other
Sumatriptan may also be called a triptan
Each 0
Sodium Chloride 7647-14-5 7 mg/vial Water for Injection 7732-18-5 Quantity Sufficient SECTION 4 : FIRST AID MEASURES Eye Contact: Immediately flush eyes with plenty of water for at least 15 to 20 Common side effects of SUMAtriptan Succinate Syringe may include: numbness, tingling, warmth, redness, or burning sensation; pressure or heavy feeling in any part of your body; dizziness, drowsiness, feeling weak or tired; neck pain or stiffness; or
Individual Revision Bulletin 2 Sumatriptan Official March 1, 2011 M r2 = molecular weight of sumatriptan succinate, • USP REFERENCE STANDARDS 〈11〉 413
Neck stiffness
Sumatriptan has caused serious side effects in some people, especially people who have heart or blood vessel disease
Sumatriptan succinate tablets are contraindicated in patients with: Ischemic coronary artery disease (CAD) (angina pectoris, history of myocardial infarction, or documented silent ischemia) or coronary artery vasospasm, including Prinzmetal's angina [see Warnings and Precautions (5
tingling in the hands and feet
In the present work Sumatriptan succinate, an antimigraine drug having bitter taste is masked and orally disintegrating tablets Sumatriptan is not recommended for use in people aged over 65 years
4 mg of sumatriptan succinate, USP equivalent to 6 mg of sumatriptan and 3
The prepared niosomes were evaluated for entrapment efficiency, size analysis and in vitro release studies
Sumatriptan succinate is a 5HT 1D-Serotonin receptor agonist
Sumatriptan Succinate is chemically described as methylmethanesulphonamide hydrogen butanedioate
Dosage Form; Route: Injectable; subcutaneous
Overview: The Reference (R) product is a drug-device combination product
Emergency telephone number: CHEMTREC (24 hours): 1-800-424-9300 Contact E-Mail: pfizer-MSDS@pfizer
Additional comments: (1) Subjects should adhere to the R product labeling for administration
Sumatriptan succinate (C 18 H 27 N 3 O 6 S) has a molecular weight of 413
Thus, it is not an ideal candidate for transdermal patch Fig
Ischemic coronary artery disease (CAD) (angina pectoris, history of myocardial infarction, or documented silent ischemia) or coronary artery vasospasm, including The empirical formula is C 14 H 21 N 3 O 2 S•C 4 H 6 O 4, representing a molecular weight of 413
This is not a complete list of side effects and others may occur Download DRUG LABEL INFO: PDF XML; Official Label (Printer Friendly) View All Sections Close All Sections
The pH range of the solution is Examples of mild side effects that have been reported with sumatriptan include: feeling warm or cold
But, it's possible that you can take it again 2 hours after the first dose if your migraine doesn't go away
The tablets are supplied in bottles of 30, 36, 90, 100, 500 and unit of use blister pack of 9's and 27's
It does not contain all of the available information
Figures
IMITREX (sumatriptan) injection, for subcutaneous use Initial U
Generic name: sumatriptan succinate
SUMATRIPTAN INJECTION is not intended for
If you get some relief, or if the migraine comes back after being relieved, another dose may be taken 2 hours after the
Test solution— Transfer about 70 mg of Sumatriptan Succinate, accurately weighed, to a 25-mL volumetric flask, dissolve in and dilute with Mobile phase to volume, and mix
The sumatriptan oral tablet (Imitrex) is used to treat migraine headaches
Sumatriptan injection, is not indicated for the prevention of migraine
[NOTE—Sonicate if necessary
1
8 Sumatriptan This information from Lexicomp explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider
Download DRUG LABEL INFO: PDF XML; Official Label (Printer Friendly) View All Sections Close All Sections
6-mm × 25-cm column that contains 5-µm
tingling in the hands and feet
In the present work Sumatriptan succinate, an antimigraine drug having bitter taste is
5 mL of sumatriptan injection, USP solution contains 8
Niosomes of sumatriptan succinate were prepared using lipid hydration method
96 %
Freely soluble in water, sparingly soluble
Emergency telephone number: CHEMTREC (24 hours): 1-800-424-9300 Contact E-Mail: pfizer-MSDS@pfizer
The maximum recommended dose that may be given in 24 hours is two doses of Sumavel DosePro (or one dose of Sumavel Dosepro and one dose of another sumatriptan product), separated by
determined that the needle height and Sumatriptan succinate is chemically designated as 3-[2- (dimethylamino) ethyl]-N-methyl-indole-5-methanesulfonamide succinate (1:1), and it has the following structure: The molecular formula is C 14 H 21 N 3 O 2 S•C 4 H 6 O 4, representing a molecular weight of 413
By intranasal administration
2 shows the LC-MS total ion chromatogram from acid degradation of sumatriptan after 10 h at 90°C
Sumatriptan injection, is not indicated for the prevention of migraine or cluster headache attacks