The number of cells in this community is tightly regulated—not simply by controlling the rate of cell division, but also by controlling the rate of cell death
The 500 mg dosage form is a white to off-white, modified capsule shaped, film-coated tablet, imprinted with “P” and “413” on one side and bisected on the other side
UDCA was Food and Drug Administration (FDA) approved for cholesterol gall stone dissolution, and primary
The possible mechanisms of action include stimulation of hepatocellular and ductular secretions, expansion of hydrophilic bile acid pool, membrane stabilizing effect, anti-inflammatory, antioxidant and immune modulation effect
Several ion channels in the plasma membrane, in particular the N-type K+ channel, the chloride channel cystic fibrosis conductance
Caspases are a family of cysteine proteases, and the key factors behind the cellular events which occur during apoptosis and inflammation
It is used during early development to eliminate unwanted cells; for example, those between the fingers of a developing hand
In biology, many substances are hydrophilic, which allows them to be dispersed throughout a cell or organism
It is used, in contrast to necrosis, to describe the situation in which a cell actively pursues a course toward death upon receiving certain stimuli []
In cholestatic liver disease, the toxic BAs, which make up a majority of bile acids in humans, begin to accumulate within hepatocytes
Proceedings of the National Academy of Sciences USA , published online Understanding apoptosis pathways for cancer therapeutics The word cancer was first named by a physician Hippocrates around 460-370 B
It has a role in biological processes, including embryogenesis, ageing, and many diseases
In Humans, UDCA accounts for up to 3–4% of the bile acid pool; it is formed by epimerization of 7α-hydroxy-CDCA in the gut by intestinal bacteria and represents the
[PMC free article The intrinsic pathway of apoptosis pathway begins when an injury occurs within the cell and the resulting stress activates the apoptotic pathway