Domperidone pharmacokinetics

1 g Suspension Oral 100 mg Solution / drops Oral 1 % Suppository Rectal 60 MG Syrup Oral. It has no clinically significant interaction with the D 1 receptor, unlike metoclopramide

2024-03-29
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  1. Dopamine Antagonists
  2. Metabolites are excreted in urine and feces
  3. On the pharmacokinetics of domperidone in animals and man
  4. 0 h after the morning dose on domperidone alone, and 5
  5. 63) and 15
  6. 2014 Mar;3 (2):126-31
  7. This is presumably due to a high first-pass effect
  8. Eur J Drug Metab Pharmacokinet 1981;6: 61-70
  9. ) domperidone (20 mg/kg) alone or together with piperine (20 mg/kg, p
  10. Pharmacokinetics Pharmacokinetics
  11. A specific blocker of dopamine receptors
  12. Sample preparation was accomplished through prote
  13. Healthy subjects (14 men, 10 women; age 18-39 years; mean weight 73
  14. administration of the labelled compound at 2
  15. 1990 May;9 (5):357-65
  16. Methods An oral domperidone solution was administered (0
  17. Domperidone has a plasma half-life of 7–9 h
  18. ) or intraperitoneal (i
  19. Davis Drug Guide PDF
  20. agonists
  21. This combination may Simcyp V13
  22. Plasma concentrations peaked within 2 h after each dose
  23. 8-98
  24. 5 mg/kg