It is approved for the treatment of bipolar disorder (also known as manic depression) and certain types of seizure disorders
Recent data shows that Lamictal may have additional effects on other neurotransmitters, such as serotonin and dopamine, which play a role in mood regulation
The total radioactivity detected after a 240mg radiolabeled dose of lamotrigine during clinical trials were as follows: lamotrigine as unchanged drug (10%), a 2-N-glucuronide
It may also be used to help prevent the extreme mood swings of bipolar disorder in
Lamotrigine (la moe' tri jeen) is a phenyltriazine and belongs to an anticonvulsant class of its own
Glutamate, the major excitatory neurotransmitter in the central nervous system, and glutamatergic dysfunction has been implicated in mood disorders
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How does lamotrigine work in the brain for bipolar? Lamotrigine works by inhibiting cell pathways in the brain called sodium channels, which reduces the emission of chemicals called glutamate and aspartate, two of the most important excitatory neurotransmitters in the brain
Glutamate is the major excitatory neurotransmitter in the central nervous system (CNS) and plays a central role in synaptic plasticity, learning, and memory
Lamictal, also known by its generic name lamotrigine, is a medication commonly prescribed for the treatment of epilepsy and bipolar disorder
Lamictal is rapidly absorbed and peak levels are reached within 1
Amino acids like tryptophan and tyrosine are precursors to neurotransmitters serotonin and dopamine, respectively, influencing mood, cognition, and behavior
Lamictal is also used to control seizures in people
It does this by inhibiting sodium channels, which reduces the release of glutamate—an excitatory neurotransmitter that can cause seizures when present in excessive amounts
Most commonly, mood stabilizers are used to treat those with bipolar disorder
These messages help you move your limbs, feel sensations, keep your heart beating, and take in and respond to all information your body receives from other internal parts of Lamictal is used alone or with other medications to treat epileptic seizures in adults and children
Lamotrigine is an anti-convulsant, which means it is often prescribed as a treatment for epilepsy 1 2
Like most antidepressants, cyclic antidepressants work by ultimately effecting changes in brain chemistry and communication in brain nerve cell circuitry known to regulate mood, to help relieve