However, whether GCV and/or ACV phosphorylation in Ep
With increasing use of acyclovir and ganciclovir, primarily due to the increased number of AIDS and transplant patients, further cases of neurologic toxicity will undoubtedly be encountered
Ganciclovir is used to treat the symptoms of cytomegalovirus (CMV) infection of the
Ganciclovir is a prodrug that is structurally similar to acyclovir
g
An analysis of the action mechanism of known antiviral drugs concluded that they can increase the cell’s resistance to a virus (interferons), suppress the virus
Metabolism and antiviral action
Several case reports have documented preservation of vision in patients treated with a combination of intravenous ganciclovir
15% with ACV 3% ointment found that ganciclovir is as effective as acyclovir
This product is available in the following dosage forms: In deciding to use Ganciclovir ophthalmic dosing information
It has recently been released as a new topical antiviral gel in humans
[32676] [61771] Although not specifically contraindicated by the manufacturer, ganciclovir ophthalmic gel should be used with extreme caution in these patients as well
The Pediatric AIDS Clinical Trials Group
The major adverse effects of ganciclovir therapy include fever, rash, diarrhea, and hematologic effects (ie
The use of acyclovir for cytomegalovirus infections in the immunocompromised host
GCV and ACV must be monophosphorylated by virally encoded enzymes to be converted into nucleotides and incorporated into viral DNA
Acyclovir (ACV Ganciclovir (9-(1,3-dihydroxy-2-propoxymethyl) guanine, DHPG) is an acyclovir analog with excellent antiviral activity against human cytomegalovirus (CMV)
As acyclovir and ganciclovir inhibit EBV in vitro [11,34,35], these drugs and their oral prodrugs were evaluated for suppression of EBV reactivation during immunosuppression
Acyclovir is used to treat infections caused by herpes viruses, such as genital herpes, cold sores, shingles, and chicken pox
4 ), although it is also as active as acyclovir against HSV-1 and HSV-2 and almost as active against VZV