Children 2 to 4 years of age—Dose is based on body weight and must be determined by your doctor
Overview
Less than 6 years of age: Initial dose: 10 to 20 mg/kg/day orally in 2 to 3 divided doses (immediate-release [IR] tablets), 4 divided doses (oral suspension), OR every 12 hours (extended-release capsules) Increase dose at weekly intervals (maintain divided doses) to achieve optimal clinical response Patients receiving concomitant AEDs may be converted to monotherapy by initiating treatment with TRILEPTAL at 600 mg/day (given in a twice a day
In pediatric patients aged 2 to <4 years, initiate TRILEPTAL at a daily dose of 8 to 10 mg/kg generally not to exceed 600 mg/day, given twice-a-day
In pediatric patients aged 2-<4 years, treatment should also be initiated at a daily dose of 8-10 mg/kg generally not to exceed 600 mg/day, given in a twice-a-day regimen
Withdraw concomitant AEDs completely over 3 to 6 weeks, while increasing the oxcarbazepine dose in increments of 600 mg/day at weekly intervals up to target
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Adults and children 17 years of age and older—At first, 300 milligrams (mg) 2 times a day
For patients less than 20 kg, a starting dose of 16 to 20 mg/kg may be considered [see Clinical Pharmacology (12
The starting dose is 8 to 10 mg per kg of body weight per day, divided into 2 doses
For patients less than 20 kg, a starting dose of 16 to 20 mg/kg may be considered [ see Clinical Pharmacology (12
In clinical trials in pediatric patients 2–4 years of age, target dosage was 60 mg/kg daily; however, only 50% of patients reached a final dosage of ≥55 mg/kg daily
The target maintenance dose of Trileptal for adjunctive therapy is 3046 mg/kg/day and should be - achieved over two weeks
Detailed dosage guidelines and administration information for Oxtellar XR (oxcarbazepine)
A 10 ml oral dosing syringe and a press-in adapter for the syringe are provided by the manufacturer with each bottle
1 Partial seizures; 2
pounding, slow heartbeat
Partial-onset seizures, adjunctive therapy: Oral: Immediate release (Trileptal): Children 2 to <4 years: The Oxcarbazepine is usually given twice each day
5 mg/kg/day)
Morning dosing was then added, as needed, up to the maximum dose reported per patient
sleepiness
Because Trileptal’s safety profile in children is promising, its levels don’t fluctuate due to liver enzyme induction, it The patients receiving high dose valproate had greater improvements in their global severity rating score without a significant difference in tolerability to the valproate