From the studies done so far, it can be concluded that brexpiprazole can be an effective monotherapy for schizophrenia and as an adjunct to other antidepressant medications in
Abilify (aripiprazole) can be an alternative antipsychotic to Rexulti (brexpiprazole)
Compare Drugs
Abstract
Brexpiprazole is not a controlled
Although they share a similar mechanism of action, DRPAs differ in their pharmacodynamics, pharmacokinetics, drug interactions, or safety and tolerability
Feb 17, 2023 · Other outcomes included akathisia, in which brexpiprazole ranked slightly better than aripiprazole (RR 1
Both aripiprazole and brexpiprazole are metabolized via cytochrome P450 (CYP) 2D6 and CYP3A4, and thus the dose may need to be adjusted in the presence of
Both function as partial agonists of the dopamine-2 receptor (D 2 R), a mechanism of action shared with aripiprazole
Jan 15, 2019 · Brexpiprazole vs aripiprazole
May 16, 2023 · Aripiprazole is a medication used to manage and treat schizophrenia, mania associated with bipolar I disorder, irritability associated with an autism spectrum disorder, disjunctive therapy in major depressive disorder, and Tourette syndrome
52% of reviewers reported a positive effect, while 28% reported a negative
The relative intrinsic D 2 activity of brexpiprazole was 43% compared with 61% for aripiprazole, 84% for bifeprunox, and 100% for dopamine as determined by the maximum inhibitory effect on forksolin-induced cAMP in human D 2
Background: There is a need for effective, safe and well-tolerated pharmacotherapies for patients with major depressive disorder (MDD) who have inadequate response to antidepressant treatments (ADTs)
com
51% of reviewers reported a positive effect, while 36% reported a negative effect
Its impact on 5HT 1a receptors might translate into precognitive and mood-enhancing effects as well as a reduced risk of extrapyramidal symptoms (EPS)
Source: Keks N, Schwartz D, Hope J