Aug 24, 2023 · Intrauterine growth restriction and SGA are some of the most widely reported adverse outcomes from the use of beta-blockers in pregnancy
1984
Not addressed in this study, but also important to consider, is the association between
A study of a large number of pregnancies found that beta-blockers in general did not increase the chance of heart defects
analyzed data from 4
However, some aspects of
It can also reduce the risk of heart attack and
Other beta-blockers, like Coreg (carvedilol) and Inderal (propranolol), block beta receptors throughout your body
gov Because of the low levels of metoprolol in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants
A study of mothers taking beta-blockers during nursing found a numerically, but not statistically significant increased number of adverse reactions in those taking any beta-blocker
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Lower once-daily doses may not maintain full effect at the end of the 24-hour period; larger or more frequent daily doses may be required
Metoprolol belongs to a group of drugs called beta blockers, which work by relaxing blood vessels and slowing heart rate
5% in the unexposed
It works by affecting the response to nerve impulses in certain parts of the body, like the heart
In contrast to metoprolol, atenolol, a renally eliminated beta-blocker, is a potential alternative during pregnancy
2 There are limited data for calcium channel blockers, but nifedipine is commonly
Dobutamine — increased risk of severe hypertension and bradycardia when non-cardioselective beta-blockers (nadolol, pindolol, propranolol, timolol) are given with dobutamine
The most commonly prescribed medication was the beta-1-selective beta-blocker metoprolol (n = 141; 86
INTRODUCTION
Mean birth weight and % low birth weight (<2500 g) were 2926 ± 841 g and 24
FDA-approved uses of beta-1-selective blockers include hypertension, chronic stable angina, heart failure, post-myocardial infarction, and decreased left ventricular function after a recent myocardial infarction
Disposition of the adrenergic blocker metoprolol in the late pregnant woman, the amniotic fluid, the cord blood and the neonate
Clin Exp In general, beta-blockers reduce placental perfusion, which has been associated with growth retardation, intrauterine death, abortion and early labour