The main types are: Drug-drug interaction
Benadryl (diphenhydramine) CoQ10 (ubiquinone) Cymbalta (duloxetine) Fish Oil (omega-3 polyunsaturated fatty acids) Flonase (fluticasone nasal) citalopram, Zoloft, Cymbalta
Certain drugs, including some anesthetics, are known to contribute to QT prolongation
Applies to: Wellbutrin (bupropion) and diphenhydramine
What is diphenhydramine and phenylephrine? Diphenhydramine is an antihistamine
Wellbutrin could increase your risk of seizures if taking it with any medication that increases seizure threshold such as Benadryl, opioids, or clozapine
Blurred vision
Diphenhydramine (Benadryl) Opioids, like tramadol
There is no known drug interaction between Benadryl (diphenhydramine) and Wellbutrin XL (bupropion extended-release)
Wellbutrin XL (extended release): Taken once daily with at least 24 hours between doses
After 3 days, your provider might raise your dose to 150 mg twice daily with at least 8 hours between doses
The SR formulation lasts 12 hours and is taken twice a day, while the XL version lasts 24 hours and is taken once a day
Neurological effects: Tremors, restless legs, numbness, and/or difficulty walking
Prices start at $6
For seasonal affective disorder: Adults— Aplenzin®: At first, 174 milligrams (mg) once a day in the morning
Researchers estimate that side effects may occur in at least 1 in 10 people taking the drug
#MentalHealth Update: other side effects of the Wellbutrin have kicked in
, Wellbutrin SR): Initially, administer orally once daily in the morning, then increase to twice daily, in the morning and evening
Bupropion is a medication that has been used to treat depression and seasonal affective disorder
Common side effects of both drugs include dry mouth, abdominal pain, insomnia, and nausea
Although Zyban® is not indicated for treatment of depression, it contains the same active ingredient as the antidepressant medications Wellbutrin®, Wellbutrin® SR, and Wellbutrin XL®
For more information about depression, see the MotherToBaby fact sheet at Benadryl (diphenhydramine) CoQ10 (ubiquinone) Cymbalta (duloxetine) Fish Oil (omega-3 polyunsaturated fatty acids) Flonase (fluticasone nasal) citalopram, Zoloft, Cymbalta, Prozac, Wellbutrin XL, nicotine, Chantix